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OlinkAnalyze: Facilitate Analysis of Proteomic Data from Olink

A collection of functions to facilitate analysis of proteomic data from Olink, primarily NPX data that has been exported from Olink Software. The functions also work on QUANT data from Olink by log- transforming the QUANT data. The functions are focused on reading data, facilitating data wrangling and quality control analysis, performing statistical analysis and generating figures to visualize the results of the statistical analysis. The goal of this package is to help users extract biological insights from proteomic data run on the Olink platform.

Version:4.4.0
Depends:R (≥ 4.1.0)
Imports:broom,car,cli (≥ 3.6.2),dplyr (≥ 1.1.1),data.table,emmeans,forcats,generics,ggplot2,ggpubr,ggrepel, grDevices, grid,magrittr, methods,readxl,rlang,rstatix, stats,stringr,tibble,tidyr,tidyselect, tools, utils
Suggests:arrow,clusterProfiler,FSA,ggplotify,kableExtra,knitr,lme4,lmerTest,markdown,msigdbr (≥ 9.0.0),openssl,ordinal,pheatmap,rmarkdown,scales,showtext,sysfonts,systemfonts,testthat (≥ 3.3.0),umap,vdiffr,withr,zip
Published:2025-12-02
DOI:10.32614/CRAN.package.OlinkAnalyze
Author:Kathleen NevolaORCID iD [aut, cre] (kathy-nevola), Marianne SandinORCID iD [aut] (marisand), Jamey GuessORCID iD [aut] (jrguess), Simon ForsbergORCID iD [aut] (simfor), Christoffer Cambronero [aut] (Orbmac), Pascal PucholtORCID iD [aut] (AskPascal), Boxi ZhangORCID iD [aut] (boxizhang), Masoumeh Sheikhi [aut] (MasoumehSheikhi), Klev DiamantiORCID iD [aut] (klevdiamanti), Amrita Kar [aut] (amrita-kar), Lei Conze [aut] (leiliuC), Kristyn Chin [aut] (kristynchin-olink), Danai TopouzaORCID iD [aut] (dtopouza), Stephen PolloORCID iD [aut] (spollo-olprot), Kang DongORCID iD [aut] (KangD-dev), Kristian HodénORCID iD [ctb] (kristianHoden), Per ErikssonORCID iD [ctb] (b_watcher), Nicola MoloneyORCID iD [ctb], Britta LötstedtORCID iD [ctb], Emmett SprecherORCID iD [ctb], Jessica Barbagallo [ctb] (jbarbagallo), Olof Mansson [ctr] (olofmansson), Ola Caster [ctb] (OlaCaster), Olink [cph, fnd]
Maintainer:Kathleen Nevola <biostattools at olink.com>
Contact:biostattools@olink.com
License:AGPL (≥ 3)
URL:https://olink.com/https://github.com/Olink-Proteomics/OlinkRPackage
NeedsCompilation:no
Materials:NEWS
In views:Omics
CRAN checks:OlinkAnalyze results

Documentation:

Reference manual:OlinkAnalyze.html ,OlinkAnalyze.pdf
Vignettes:Calculating LOD from Olink® Explore data (source,R code)
Outlier Exclusion Vignette (source,R code)
Olink® Analyze Vignette (source,R code)
Bridging across NGS-based Olink products (source,R code)
Introduction to bridging Olink® NPX datasets (source,R code)
Plate Randomization Vignette (source,R code)

Downloads:

Package source: OlinkAnalyze_4.4.0.tar.gz
Windows binaries: r-devel:OlinkAnalyze_4.4.0.zip, r-release:OlinkAnalyze_4.4.0.zip, r-oldrel:OlinkAnalyze_4.4.0.zip
macOS binaries: r-release (arm64):OlinkAnalyze_4.4.0.tgz, r-oldrel (arm64):OlinkAnalyze_4.4.0.tgz, r-release (x86_64):OlinkAnalyze_4.4.0.tgz, r-oldrel (x86_64):OlinkAnalyze_4.4.0.tgz
Old sources: OlinkAnalyze archive

Reverse dependencies:

Reverse suggests:autonomics

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=OlinkAnalyzeto link to this page.


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