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tci: Target Controlled Infusion (TCI)

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Version:0.2.1
Depends:R (≥ 4.2.0)
Imports:ggplot2, stats, utils,mvtnorm,reshape,Rcpp,knitr
LinkingTo:Rcpp,RcppArmadillo
Suggests:testthat (≥ 2.1.0),rmarkdown,mrgsolve,gridExtra,reshape2,truncnorm,xtable
Published:2025-09-27
DOI:10.32614/CRAN.package.tci
Author:Ryan Jarrett [aut, cre]
Maintainer:Ryan Jarrett <ryantjarrett at gmail.com>
BugReports:https://github.com/jarretrt/tci/issues
License:GPL-2
URL:https://github.com/jarretrt/tci
NeedsCompilation:yes
SystemRequirements:C++17
Materials:README
CRAN checks:tci results

Documentation:

Reference manual:tci.html ,tci.pdf
Vignettes:Custom PK models and algorithms (source,R code)
Introduction to tci package (source,R code)
Population PK models (source,R code)

Downloads:

Package source: tci_0.2.1.tar.gz
Windows binaries: r-devel:tci_0.2.1.zip, r-release:tci_0.2.1.zip, r-oldrel:tci_0.2.1.zip
macOS binaries: r-release (arm64):tci_0.2.1.tgz, r-oldrel (arm64):tci_0.2.1.tgz, r-release (x86_64):tci_0.2.1.tgz, r-oldrel (x86_64):tci_0.2.1.tgz
Old sources: tci archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=tcito link to this page.


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