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apmx: Automated Population Pharmacokinetic Dataset Assembly

Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in 'NONMEM' (non-linear mixed effects modeling) by Bauer (2019) <doi:10.1002/psp4.12404>. The package includes functions to build datasets from SDTM (study data tabulation module) <https://www.cdisc.org/standards/foundational/sdtm>, ADaM (analysis dataset module) <https://www.cdisc.org/standards/foundational/adam>, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.

Version:1.1.1
Depends:R (≥ 4.00)
Imports:dplyr,tidyr,purrr,this.path,flextable,officer,tidyselect, utils,arsenal
Suggests:rmarkdown,knitr,testthat,tibble
Published:2024-01-09
DOI:10.32614/CRAN.package.apmx
Author:Stephen Amori [aut, cre, cph], Ethan DellaMaestra [aut], Michael Dick [aut], Daniel Litow [ctb], Jonah Lyon [ctb]
Maintainer:Stephen Amori <stephen.amori at amadorbio.com>
BugReports:https://github.com/stephen-amori/apmx/issues
License:GPL (≥ 3)
URL:https://github.com/stephen-amori/apmx
NeedsCompilation:no
Materials:README,NEWS
CRAN checks:apmx results

Documentation:

Reference manual:apmx.html ,apmx.pdf
Vignettes:PKPD_analysis (source,R code)

Downloads:

Package source: apmx_1.1.1.tar.gz
Windows binaries: r-devel:apmx_1.1.1.zip, r-release:apmx_1.1.1.zip, r-oldrel:apmx_1.1.1.zip
macOS binaries: r-release (arm64):apmx_1.1.1.tgz, r-oldrel (arm64):apmx_1.1.1.tgz, r-release (x86_64):apmx_1.1.1.tgz, r-oldrel (x86_64):apmx_1.1.1.tgz

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=apmxto link to this page.


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