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ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

Version:2.1.0
Depends:R (≥ 4.2.0)
Imports:cli,deSolve,dplyr (≥ 1.0.0),digest,doParallel,flextable,foreach,ggplot2,knitr,MASS,onbrand (≥ 1.0.2),optimx,PKNCA,pso,readxl,rmarkdown,rhandsontable,scales, stats,stringr,shiny
Suggests:babelmixr2,GA,GGally,gridGraphics,gridExtra, grid,officer,rxode2,webshot,ggrepel,rstudioapi,testthat
Published:2025-01-07
DOI:10.32614/CRAN.package.ubiquity
Author:John HarroldORCID iD [aut, cre]
Maintainer:John Harrold <john.m.harrold at gmail.com>
BugReports:https://github.com/john-harrold/ubiquity/issues
License:BSD_2_clause + fileLICENSE
URL:https://r.ubiquity.tools
NeedsCompilation:no
SystemRequirements:Perl
Citation:ubiquity citation info
Materials:README,NEWS
In views:Pharmacokinetics
CRAN checks:ubiquity results

Documentation:

Reference manual:ubiquity.html ,ubiquity.pdf
Vignettes:Deployment (source,R code)
Estimation (source,R code)
Language (source,R code)
Report Generation (source,R code)
Simulation (source,R code)
Titration/Rule-Based Simulations (source,R code)

Downloads:

Package source: ubiquity_2.1.0.tar.gz
Windows binaries: r-devel:ubiquity_2.1.0.zip, r-release:ubiquity_2.1.0.zip, r-oldrel:ubiquity_2.1.0.zip
macOS binaries: r-release (arm64):ubiquity_2.1.0.tgz, r-oldrel (arm64):ubiquity_2.1.0.tgz, r-release (x86_64):ubiquity_2.1.0.tgz, r-oldrel (x86_64):ubiquity_2.1.0.tgz
Old sources: ubiquity archive

Reverse dependencies:

Reverse suggests:ruminate

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=ubiquityto link to this page.


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