Bayesian models to estimate causal effects of biological treatments on time-to-event endpoints in clinical trials with principal strata defined by the occurrence of antidrug antibodies. The methodology is based on Frangakis and Rubin (2002) <doi:10.1111/j.0006-341x.2002.00021.x> and Imbens and Rubin (1997) <doi:10.1214/aos/1034276631>, and here adapted to a specific time-to-event setting.
| Version: | 0.0.7 |
| Depends: | R (≥ 3.4.0) |
| Imports: | dplyr,furrr,magrittr, methods,purrr,Rcpp (≥ 0.12.0),RcppParallel (≥ 5.0.1),rstan (≥ 2.18.1),rstantools (≥2.4.0), stats,stringr,tibble |
| LinkingTo: | BH (≥ 1.66.0),Rcpp (≥ 0.12.0),RcppEigen (≥ 0.3.3.3.0),RcppParallel (≥ 5.0.1),rstan (≥ 2.18.1),StanHeaders (≥2.18.0) |
| Suggests: | spelling |
| Published: | 2024-04-13 |
| DOI: | 10.32614/CRAN.package.BPrinStratTTE |
| Author: | Christian Stock [aut, cre], Emma Torrini [aut], Boehringer Ingelheim Pharma GmbH & Co. KG [cph, fnd] |
| Maintainer: | Christian Stock <christian.stock at boehringer-ingelheim.com> |
| BugReports: | https://github.com/Boehringer-Ingelheim/BPrinStratTTE/issues |
| License: | GPL (≥ 3) |
| URL: | https://github.com/Boehringer-Ingelheim/BPrinStratTTE,https://boehringer-ingelheim.github.io/BPrinStratTTE/ |
| NeedsCompilation: | yes |
| SystemRequirements: | GNU make |
| Language: | en-US |
| Materials: | README,NEWS |
| CRAN checks: | BPrinStratTTE results |