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gfoRmula: Parametric G-Formula

Implements the non-iterative conditional expectation (NICE) algorithm of the g-formula algorithm (Robins (1986) <doi:10.1016/0270-0255(86)90088-6>, Hernán and Robins (2024, ISBN:9781420076165)). The g-formula can estimate an outcome's counterfactual mean or risk under hypothetical treatment strategies (interventions) when there is sufficient information on time-varying treatments and confounders. This package can be used for discrete or continuous time-varying treatments and for failure time outcomes or continuous/binary end of follow-up outcomes. The package can handle a random measurement/visit process and a priori knowledge of the data structure, as well as censoring (e.g., by loss to follow-up) and two options for handling competing events for failure time outcomes. Interventions can be flexibly specified, both as interventions on a single treatment or as joint interventions on multiple treatments. See McGrath et al. (2020) <doi:10.1016/j.patter.2020.100008> for a guide on how to use the package.

Version:1.1.1
Depends:R (≥ 3.5.0)
Imports:data.table,ggplot2,ggpubr, grDevices,nnet, parallel,progress, stats,stringr,survival,truncnorm,truncreg, utils
Suggests:Hmisc,knitr,randomForest,rmarkdown,testthat (≥ 3.0.0)
Published:2025-03-24
DOI:10.32614/CRAN.package.gfoRmula
Author:Victoria Lin [aut] (V. Lin and S. McGrath made equal contributions), Sean McGrathORCID iD [aut, cre] (V. Lin and S. McGrath made equal contributions), Zilu Zhang [aut], Roger W. Logan [aut], Lucia C. Petito [aut], Jing Li [aut], McGee EmmaORCID iD [aut], Cheng Carrie [aut], Jessica G. YoungORCID iD [aut] (M.A. Hernán and J.G. Young made equal contributions), Miguel A. Hernán [aut] (M.A. Hernán and J.G. Young made equal contributions), 2019 The President and Fellows of Harvard College [cph]
Maintainer:Sean McGrath <sean.mcgrath514 at gmail.com>
BugReports:https://github.com/CausalInference/gfoRmula/issues
License:GPL-3
URL:https://github.com/CausalInference/gfoRmula,https://doi.org/10.1016/j.patter.2020.100008
NeedsCompilation:no
Materials:README,NEWS
In views:CausalInference
CRAN checks:gfoRmula results

Documentation:

Reference manual:gfoRmula.html ,gfoRmula.pdf
Vignettes:Using Custom Outcome Models in gfoRmula (source,R code)
A Simplified Approach for Specifying Interventions in gfoRmula (source,R code)

Downloads:

Package source: gfoRmula_1.1.1.tar.gz
Windows binaries: r-devel:gfoRmula_1.1.1.zip, r-release:gfoRmula_1.1.1.zip, r-oldrel:gfoRmula_1.1.1.zip
macOS binaries: r-release (arm64):gfoRmula_1.1.1.tgz, r-oldrel (arm64):gfoRmula_1.1.1.tgz, r-release (x86_64):gfoRmula_1.1.1.tgz, r-oldrel (x86_64):gfoRmula_1.1.1.tgz
Old sources: gfoRmula archive

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