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BIGDAWG: Case-Control Analysis of Multi-Allelic Loci

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Version:3.0.3
Depends:R (≥ 3.5.0)
Imports:XML,httr,haplo.stats, parallel
Suggests:knitr,rmarkdown
Published:2021-11-17
DOI:10.32614/CRAN.package.BIGDAWG
Author:Derek Pappas, Steve Mack, Jill Hollenbach
Maintainer:Steve Mack <Steven.Mack at ucsf.edu>
BugReports:https://github.com/IgDAWG/BIGDAWG/issues
License:GPL (≥ 3)
URL:http://tools.immunogenomics.org/,https://github.com/IgDAWG/BIGDAWG
NeedsCompilation:no
Materials:NEWS
CRAN checks:BIGDAWG results

Documentation:

Reference manual:BIGDAWG.html ,BIGDAWG.pdf
Vignettes:BIGDAWG (source)
GLSconvert (source)

Downloads:

Package source: BIGDAWG_3.0.3.tar.gz
Windows binaries: r-devel:BIGDAWG_3.0.3.zip, r-release:BIGDAWG_3.0.3.zip, r-oldrel:BIGDAWG_3.0.3.zip
macOS binaries: r-release (arm64):BIGDAWG_3.0.3.tgz, r-oldrel (arm64):BIGDAWG_3.0.3.tgz, r-release (x86_64):BIGDAWG_3.0.3.tgz, r-oldrel (x86_64):BIGDAWG_3.0.3.tgz
Old sources: BIGDAWG archive

Reverse dependencies:

Reverse imports:pould

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=BIGDAWGto link to this page.


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