A model building aid for nonlinear mixed-effects (population) model analysis using NONMEM, facilitating data set checkout, exploration and visualization, model diagnostics, candidate covariate identification and model comparison. The methods are described in Keizer et al. (2013) <doi:10.1038/psp.2013.24>, and Jonsson et al. (1999) <doi:10.1016/s0169-2607(98)00067-4>.
| Version: | 4.7.4 |
| Depends: | R (≥ 2.2.0),lattice |
| Imports: | Hmisc,survival,dplyr,tibble, methods,lazyeval,gam, splines, grid,readr |
| Suggests: | testthat |
| Published: | 2025-09-03 |
| DOI: | 10.32614/CRAN.package.xpose4 |
| Author: | Andrew C. Hooker [aut, cre, cph], Mats O. Karlsson [aut, cph], Justin J. Wilkins [aut], E. Niclas Jonsson [aut, trl, cph], Ron Keizer [ctb] (functionality for bootstrap of GAM and SCM) |
| Maintainer: | Andrew C. Hooker <andrew.hooker at uu.se> |
| BugReports: | https://github.com/UUPharmacometrics/xpose4/issues |
| License: | LGPL (≥ 3) |
| Copyright: | 2009-2025 Andrew C. Hooker, E. Niclas Jonsson and Mats O.Karlsson. 2005-2008 Andrew C. Hooker, Justin J. Wilkins, MatsO. Karlsson and E. Niclas Jonsson. 1998-2004 E. Niclas Jonssonand Mats Karlsson. |
| URL: | https://uupharmacometrics.github.io/xpose4/,https://github.com/UUPharmacometrics/xpose4 |
| NeedsCompilation: | no |
| Citation: | xpose4 citation info |
| Materials: | README,NEWS |
| In views: | Pharmacokinetics |
| CRAN checks: | xpose4 results |