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depower: Power Analysis for Differential Expression Studies

Provides a convenient framework to simulate, test, power, and visualize data for differential expression studies with lognormal or negative binomial outcomes. Supported designs are two-sample comparisons of independent or dependent outcomes. Power may be summarized in the context of controlling the per-family error rate or family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) <doi:10.1186/s12859-017-1648-2> and Yu, Fernandez, and Brock (2020) <doi:10.1186/s12859-020-3541-7>.

Version:2025.10.21
Depends:R (≥ 4.2.0)
Imports:Rdpack, stats,mvnfast,glmmTMB,dplyr,multidplyr,ggplot2,scales
Suggests:tinytest,rmarkdown
Published:2025-10-22
DOI:10.32614/CRAN.package.depower
Author:Brett KlamerORCID iD [aut, cre], Lianbo YuORCID iD [aut]
Maintainer:Brett Klamer <code at brettklamer.com>
License:MIT + fileLICENSE
URL:https://brettklamer.com/work/depower/,https://bitbucket.org/bklamer/depower/
NeedsCompilation:no
Language:en-US
Citation:depower citation info
Materials:README,NEWS
CRAN checks:depower results

Documentation:

Reference manual:depower.html ,depower.pdf

Downloads:

Package source: depower_2025.10.21.tar.gz
Windows binaries: r-devel:depower_2025.10.21.zip, r-release:depower_2025.10.21.zip, r-oldrel:depower_2025.10.21.zip
macOS binaries: r-release (arm64):depower_2025.10.21.tgz, r-oldrel (arm64):depower_2025.10.21.tgz, r-release (x86_64):depower_2025.10.21.tgz, r-oldrel (x86_64):depower_2025.10.21.tgz
Old sources: depower archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=depowerto link to this page.


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