ClussCluster: Simultaneous Detection of Clusters and Cluster-Specific Genes inHigh-Throughput Transcriptome Data
Implements a new method 'ClussCluster' descried in Ge Jiang and Jun Li, "Simultaneous Detection of Clusters and Cluster-Specific Genes in High-throughput Transcriptome Data" (Unpublished).Simultaneously perform clustering analysis and signature gene selection on high-dimensional transcriptome data sets. To do so, 'ClussCluster' incorporates a Lasso-type regularization penalty term to the objective function of K-means so that cell-type-specific signature genes can be identified while clustering the cells.
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