hesim: Health Economic Simulation Modeling and Decision Analysis
A modular and computationally efficient R package for parameterizing, simulating, and analyzing health economic simulation models. The package supports cohort discrete time state transition models (Briggs et al. 1998) <doi:10.2165/00019053-199813040-00003>, N-state partitioned survival models (Glasziou et al. 1990) <doi:10.1002/sim.4780091106>, and individual-level continuous time state transition models (Siebert et al. 2012) <doi:10.1016/j.jval.2012.06.014>, encompassing both Markov (time-homogeneous and time-inhomogeneous) and semi-Markov processes. Decision uncertainty from a cost-effectiveness analysis is quantified with standard graphical and tabular summaries of a probabilistic sensitivity analysis (Claxton et al. 2005, Barton et al. 2008) <doi:10.1002/hec.985>, <doi:10.1111/j.1524-4733.2008.00358.x>. Use of C++ and data.table make individual-patient simulation, probabilistic sensitivity analysis, and incorporation of patient heterogeneity fast.
| Version: | 0.5.7 |
| Depends: | R (≥ 3.5.0) |
| Imports: | data.table,flexsurv,ggplot2,MASS,msm,Rcpp (≥ 0.12.16),R6, stats,survival |
| LinkingTo: | Rcpp,RcppArmadillo |
| Suggests: | covr,kableExtra,knitr,magrittr,mstate,nnet,numDeriv,pracma,rmarkdown,scales,testthat,truncnorm |
| Published: | 2025-10-11 |
| DOI: | 10.32614/CRAN.package.hesim |
| Author: | Devin Incerti [aut, cre], Jeroen P. Jansen [aut], Mark Clements [aut], R Core Team [ctb] (hesim uses some slightly modified C functions from base R) |
| Maintainer: | Devin Incerti <devin.incerti at gmail.com> |
| BugReports: | https://github.com/hesim-dev/hesim/issues |
| License: | GPL-3 |
| URL: | https://hesim-dev.github.io/hesim/,https://github.com/hesim-dev/hesim |
| NeedsCompilation: | yes |
| Citation: | hesim citation info |
| Materials: | README |
| CRAN checks: | hesim results |
Documentation:
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