RobinCar2: ROBust INference for Covariate Adjustment in Randomized ClinicalTrials
Performs robust estimation and inference when using covariate adjustment and/or covariate-adaptive randomization in randomized controlled trials. This package is trimmed to reduce the dependencies and validated to be used across industry. See "FDA's final guidance on covariate adjustment"<https://www.regulations.gov/docket/FDA-2019-D-0934>, Tsiatis (2008) <doi:10.1002/sim.3113>, Bugni et al. (2018) <doi:10.1080/01621459.2017.1375934>, Ye, Shao, Yi, and Zhao (2023)<doi:10.1080/01621459.2022.2049278>, Ye, Shao, and Yi (2022)<doi:10.1093/biomet/asab015>, Rosenblum and van der Laan (2010)<doi:10.2202/1557-4679.1138>, Wang et al. (2021)<doi:10.1080/01621459.2021.1981338>, Ye, Bannick, Yi, and Shao (2023)<doi:10.1080/24754269.2023.2205802>, and Bannick, Shao, Liu, Du, Yi, and Ye (2024)<doi:10.48550/arXiv.2306.10213>.
| Version: | 0.2.1 |
| Depends: | R (≥ 3.6) |
| Imports: | checkmate,numDeriv,MASS,sandwich, stats,survival, utils |
| Suggests: | knitr,rmarkdown,testthat (≥ 3.0) |
| Published: | 2025-09-11 |
| DOI: | 10.32614/CRAN.package.RobinCar2 |
| Author: | Liming Li [aut, cre], Marlena Bannick [aut], Daniel Sabanes Bove [aut], Dong Xi [aut], Ting Ye [aut], Yanyao Yi [aut], Gregory Chen [ctb], Gilead Sciences, Inc. [cph, fnd], F. Hoffmann-La Roche AG [cph, fnd], Merck Sharp & Dohme, Inc. [cph, fnd], AstraZeneca plc [cph, fnd], Eli Lilly and Company [cph, fnd], Novartis Pharma AG [cph, fnd], The University of Washington [cph, fnd] |
| Maintainer: | Liming Li <liming.li1 at astrazeneca.com> |
| BugReports: | https://github.com/openpharma/RobinCar2/issues |
| License: | Apache License 2.0 |
| URL: | https://github.com/openpharma/RobinCar2/ |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | NEWS |
| CRAN checks: | RobinCar2 results |
Documentation:
| Reference manual: | RobinCar2.html ,RobinCar2.pdf |
| Vignettes: | Package Introduction (source,R code) |
Downloads:
| Package source: | RobinCar2_0.2.1.tar.gz |
| Windows binaries: | r-devel:RobinCar2_0.2.1.zip, r-release:RobinCar2_0.2.1.zip, r-oldrel:RobinCar2_0.2.1.zip |
| macOS binaries: | r-release (arm64):RobinCar2_0.2.1.tgz, r-oldrel (arm64):RobinCar2_0.2.1.tgz, r-release (x86_64):RobinCar2_0.2.1.tgz, r-oldrel (x86_64):RobinCar2_0.2.1.tgz |
| Old sources: | RobinCar2 archive |
Linking:
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