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PRECAST: Embedding and Clustering with Alignment for Spatial OmicsDatasets

An efficient data integration method is provided for multiple spatial transcriptomics data with non-cluster-relevant effects such as the complex batch effects. It unifies spatial factor analysis simultaneously with spatial clustering and embedding alignment, requiring only partially shared cell/domain clusters across datasets. More details can be referred to Wei Liu, et al. (2023) <doi:10.1038/s41467-023-35947-w>.

Version:1.8
Depends:parallel,gtools, R (≥ 4.0.0)
Imports:MASS,Matrix,mclust, methods,purrr, utils,Seurat,irlba,cowplot,patchwork,scater,pbapply,ggthemes,dplyr,ggplot2, stats,harmony,DR.SC,scales,ggpubr, graphics,colorspace,Rcpp (≥ 1.0.5)
LinkingTo:Rcpp,RcppArmadillo
Suggests:knitr,rmarkdown
Published:2025-12-15
DOI:10.32614/CRAN.package.PRECAST
Author:Wei Liu [aut, cre], Yi Yang [aut], Jin Liu [aut]
Maintainer:Wei Liu <liuweideng at gmail.com>
BugReports:https://github.com/feiyoung/PRECAST/issues
License:GPL-3
URL:https://github.com/feiyoung/PRECAST
NeedsCompilation:yes
Materials:README
CRAN checks:PRECAST results

Documentation:

Reference manual:PRECAST.html ,PRECAST.pdf
Vignettes:PRECAST: Human Breast Cancer Data Analysis (source,R code)
PRECAST: DLPFC Single Sample Analysis (source,R code)
PRECAST: Four DLPFC Sample Analysis (source,R code)
PRECAST (source,R code)
PRECAST: simulation (source,R code)

Downloads:

Package source: PRECAST_1.8.tar.gz
Windows binaries: r-devel:PRECAST_1.7.zip, r-release:PRECAST_1.7.zip, r-oldrel:PRECAST_1.7.zip
macOS binaries: r-release (arm64):PRECAST_1.8.tgz, r-oldrel (arm64):PRECAST_1.7.tgz, r-release (x86_64):PRECAST_1.8.tgz, r-oldrel (x86_64):PRECAST_1.8.tgz
Old sources: PRECAST archive

Reverse dependencies:

Reverse imports:coFAST,ProFAST

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=PRECASTto link to this page.


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