invivoPKfit: Fits Toxicokinetic Models to In Vivo PK Data Sets
Takes in vivo toxicokinetic concentration-time data and fits parameters of 1-compartment and 2-compartment models for each chemical. These methods are described in detail in "Informatics for Toxicokinetics" (2025).
| Version: | 2.0.2 |
| Depends: | R (≥ 4.1.0) |
| Imports: | cli,dplyr,ggplot2,httk,MASS,Matrix,mirai,numDeriv,optimx,PK,pracma,purrr,rlang, stats,scales,tibble,tidyr |
| Suggests: | cowplot,knitr,RColorBrewer,rmarkdown,stringr,testthat (≥ 3.0.0),glue,tidyverse |
| Published: | 2025-08-26 |
| DOI: | 10.32614/CRAN.package.invivoPKfit |
| Author: | John Wambaugh [aut, cre], Caroline Ring [aut], Gilberto Padilla Mercado [aut], Chris Cook [aut] |
| Maintainer: | John Wambaugh <wambaugh.john at epa.gov> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| CRAN checks: | invivoPKfit results |
Documentation:
Downloads:
| Package source: | invivoPKfit_2.0.2.tar.gz |
| Windows binaries: | r-devel:invivoPKfit_2.0.2.zip, r-release:invivoPKfit_2.0.2.zip, r-oldrel:invivoPKfit_2.0.2.zip |
| macOS binaries: | r-release (arm64):invivoPKfit_2.0.2.tgz, r-oldrel (arm64):invivoPKfit_2.0.2.tgz, r-release (x86_64):invivoPKfit_2.0.2.tgz, r-oldrel (x86_64):invivoPKfit_2.0.2.tgz |
| Old sources: | invivoPKfit archive |
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