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ASSISTant: Adaptive Subgroup Selection in Group Sequential Trials

Clinical trial design for subgroup selection in three-stage group sequential trial as described in Lai, Lavori and Liao (2014, <doi:10.1016/j.cct.2014.09.001>). Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette.

Version:1.4.3
Imports:R6,mvtnorm,knitr,magrittr,dplyr
Suggests:rmarkdown
Published:2022-12-02
DOI:10.32614/CRAN.package.ASSISTant
Author:Tze Leung Lai [ctb], Philip Lavori [aut], Olivia Liao [aut], Balasubramanian Narasimhan [aut, cre], Ka Wai Tsang [aut]
Maintainer:Balasubramanian Narasimhan <naras at stat.Stanford.EDU>
BugReports:https://github.com/bnaras/ASSISTant/issues
License:GPL-2 |GPL-3 [expanded from: GPL (≥ 2)]
URL:https://github.com/bnaras/ASSISTant
NeedsCompilation:no
Materials:README,NEWS
In views:ClinicalTrials
CRAN checks:ASSISTant results

Documentation:

Reference manual:ASSISTant.html ,ASSISTant.pdf
Vignettes:Adaptive Subgroup Selection in Sequential Trials (source,R code)
Design of the DEFUSE3 Trial (source,R code)
Using Discrete Rankin Scores (source,R code)

Downloads:

Package source: ASSISTant_1.4.3.tar.gz
Windows binaries: r-devel:ASSISTant_1.4.3.zip, r-release:ASSISTant_1.4.3.zip, r-oldrel:ASSISTant_1.4.3.zip
macOS binaries: r-release (arm64):ASSISTant_1.4.3.tgz, r-oldrel (arm64):ASSISTant_1.4.3.tgz, r-release (x86_64):ASSISTant_1.4.3.tgz, r-oldrel (x86_64):ASSISTant_1.4.3.tgz
Old sources: ASSISTant archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=ASSISTantto link to this page.


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