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HLAtools: Toolkit for HLA Immunogenomics

A toolkit for the analysis and management of data for genes in the so-called "Human Leukocyte Antigen" (HLA) region. Functions extract reference data from the Anthony Nolan HLA Informatics Group/ImmunoGeneTics HLA 'GitHub' repository (ANHIG/IMGTHLA) <https://github.com/ANHIG/IMGTHLA>, validate Genotype List (GL) Strings, convert between UNIFORMAT and GL String Code (GLSC) formats, translate HLA alleles and GLSCs across ImmunoPolymorphism Database (IPD) IMGT/HLA Database release versions, identify differences between pairs of alleles at a locus, generate customized, multi-position sequence alignments, trim and convert allele-names across nomenclature epochs, and extend existing data-analysis methods.

Version:1.6.3
Depends:R (≥ 3.6.0)
Imports:DescTools,dplyr,fmsb,rvest, stats,stringr,tibble, utils,xfun
Suggests:knitr,rmarkdown,testthat (≥ 3.0.0)
Published:2025-07-21
DOI:10.32614/CRAN.package.HLAtools
Author:Livia Tran [aut], Ryan Nickens [aut], Leamon Crooms IV [aut], Derek Pappas [aut], Vinh Luu [ctb], Josh Bredeweg [ctb], Steven MackORCID iD [aut, cre]
Maintainer:Steven Mack <Steven.Mack at ucsf.edu>
License:GPL (≥ 3)
URL:<https://github.com/sjmack/HLAtools>
NeedsCompilation:no
Materials:README,NEWS
CRAN checks:HLAtools results

Documentation:

Reference manual:HLAtools.html ,HLAtools.pdf
Vignettes:HLAtools (source,R code)

Downloads:

Package source: HLAtools_1.6.3.tar.gz
Windows binaries: r-devel:HLAtools_1.6.3.zip, r-release:HLAtools_1.6.3.zip, r-oldrel:HLAtools_1.6.3.zip
macOS binaries: r-release (arm64):HLAtools_1.6.3.tgz, r-oldrel (arm64):HLAtools_1.6.3.tgz, r-release (x86_64):HLAtools_1.6.3.tgz, r-oldrel (x86_64):HLAtools_1.6.3.tgz
Old sources: HLAtools archive

Reverse dependencies:

Reverse imports:SSHAARP

Linking:

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