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cophescan: Adaptation of the Coloc Method for PheWAS

A Bayesian method for Phenome-wide association studies (PheWAS) that identifies causal associations between genetic variants and traits, while simultaneously addressing confounding due to linkage disequilibrium. For details see Manipur et al (2024, Nature Communications) <doi:10.1038/s41467-024-49990-8>.

Version:1.4.2
Depends:R (≥ 3.5.0)
Imports:Rcpp (≥ 1.0.7),coloc,data.table,ggplot2,ggrepel,pheatmap, methods,viridis, stats, grDevices,magrittr, utils,matrixStats,dplyr
LinkingTo:Rcpp,RcppArmadillo
Suggests:knitr,testthat (≥ 3.0.0),rmarkdown,RColorBrewer,ggpubr
Published:2025-07-30
DOI:10.32614/CRAN.package.cophescan
Author:Ichcha Manipur [aut, cre], Chris Wallace [aut]
Maintainer:Ichcha Manipur <im504 at cam.ac.uk>
BugReports:https://github.com/ichcha-m/cophescan/issues
License:GPL-3
URL:https://github.com/ichcha-m/cophescan,https://ichcha-m.github.io/cophescan/
NeedsCompilation:yes
Citation:cophescan citation info
Materials:README,NEWS
CRAN checks:cophescan results

Documentation:

Reference manual:cophescan.html ,cophescan.pdf
Vignettes:CoPheScan: Example with Fixed Priors (source,R code)
CoPheScan: Example with Hierarchical Priors (source,R code)
CoPheScan: Input data (source,R code)
Introduction to CoPheScan (source,R code)

Downloads:

Package source: cophescan_1.4.2.tar.gz
Windows binaries: r-devel:cophescan_1.4.2.zip, r-release:cophescan_1.4.2.zip, r-oldrel:cophescan_1.4.2.zip
macOS binaries: r-release (arm64):cophescan_1.4.2.tgz, r-oldrel (arm64):cophescan_1.4.2.tgz, r-release (x86_64):cophescan_1.4.2.tgz, r-oldrel (x86_64):cophescan_1.4.2.tgz
Old sources: cophescan archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=cophescanto link to this page.


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