Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2025) <doi:10.1007/978-3-031-89669-9>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.
| Version: | 4.3.0 |
| Depends: | R (≥ 3.6.0) |
| Imports: | methods, stats, utils, graphics, tools,rlang,R6 (≥ 2.5.1),knitr (≥ 1.19),Rcpp (≥ 1.0.3) |
| LinkingTo: | Rcpp |
| Suggests: | ggplot2 (≥ 3.5.0),testthat (≥ 3.0.0),rmarkdown (≥ 1.10),rappdirs (≥ 0.3.3) |
| Published: | 2025-12-16 |
| DOI: | 10.32614/CRAN.package.rpact |
| Author: | Gernot Wassmer [aut], Friedrich Pahlke [aut, cre], Till Jensen [ctb], Daniel Sabanes Bove [ctb], Stephen Schueuerhuis [ctb], Tobias Muetze [ctb] |
| Maintainer: | Friedrich Pahlke <friedrich.pahlke at rpact.com> |
| BugReports: | https://github.com/rpact-com/rpact/issues |
| License: | LGPL-3 |
| URL: | https://www.rpact.org,https://www.rpact.com,https://docs.rpact.org,https://github.com/rpact-com/rpact,https://rpact.shinyapps.io/connect |
| NeedsCompilation: | yes |
| Language: | en-US |
| Citation: | rpact citation info |
| Materials: | README,NEWS |
| In views: | ClinicalTrials |
| CRAN checks: | rpact results |