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gsDesign 3.8.0 (December2025)

New features

• gsBoundSummary() now displays calendar time forgsNB objects from the gsDesignNB package when analysistimes are provided (@keaven, #229, #233).

Improvements

• plotgsPower() now useslinewidth insteadof deprecatedsize aesthetic forgeom_line()calls, avoiding ggplot2 (>= 3.4.0) warnings (@nanxstats, #217).

Bug fixes

• sfXG3() now correctly reports its name as “Xi-Gallo,method 3” instead of “Xi-Gallo, method 1” (@DMuriuki, #223).
• Fixed base plotting for conditional power(plottype = 4) so labels passed totext()match the plotted points. This prevents r-devel (R 4.6.0) truncationwarnings and keeps vdiffr snapshots bitwise reproducible across Rversions (@nanxstats, #231).

Testing

• Added independent unit tests forsfXG1(),sfXG2(), andsfXG3() (@DMuriuki, #223).
• Added independent unit tests fortoBinomialExact() andxtable() (@DMuriuki, #224).
• Updatedas_gt() snapshot tests for gt 1.1.0compatibility (@nanxstats, #221).
• Snapshot files are now included in the built package to satisfytestthat (>= 3.3.0) requirements (@jdblischak, #227).
• Reduced visual regression test output verbosity by wrapping basegraphics plotting expressions incapture.output() (@nanxstats, #217).

Documentation

• nNormal() now links tovignette("nNormal")in its See Also section for the full derivation and examples (@keaven, #220).

Maintenance

• Addedworkflow_dispatch trigger toR CMD check workflow for easier testing on forks (@jdblischak, #225).

gsDesign 3.7.0 (August 2025)

Breaking changes

• hGraph() has been formally removed from gsDesign(@nanxstats, #215).It was soft-deprecated in gsDesign 3.4.0 and moved to gMCPLite. UsegMCPLite::hGraph() instead.

  This change also preemptively fixes anR CMD check issuewith ggplot2 (>= 4.0.0) that would otherwise require declaring MASSas an explicit dependency (tidyverse/ggplot2#6578).

Testing

• Added independent unit tests forgsAdaptSim() andgsSimulate() (@DMuriuki, #212).
• Added independent unit tests forbinomialPowerTable()(@DMuriuki,#214).

gsDesign 3.6.9 (June 2025)

Documentation

• Added new vignettevignette("binomialTwoSample") forbinomial two-arm trial design and analysis (@keaven, #202). Covers superiority,non-inferiority, and super-superiority designs using risk-differencemethods. Includes sample size calculations, power analysis, and protocolwording with both asymptotic approximations and simulationapproaches.

New features

• New functionbinomialPowerTable() generates powertables across control rates and treatment effects. Supports bothanalytical calculations and fast simulation for exact results.

gsDesign 3.6.8 (May 2025)

Bug fixes

• gsBoundSummary() (as updated in gsDesign 3.6.6) did notconsider spending time for alternate alpha levels when thealpha argument was specified. This issue has been resolved;lsTime andusTime are now correctly used forupdated bounds with these alternate alpha levels (@keaven, #203).

Testing

• Added independent unit tests foras_gt() (@DMuriuki, #196).

Documentation

• Switched the pkgdown math renderer from KaTeX to MathJaX forimproved compatibility, as the MathJaX support was improved in pkgdown2.1.2 (@nanxstats,#200).
• Added Research Organization Registry (ROR) ID toDESCRIPTION (@jdblischak, #201).

gsDesign 3.6.7 (March 2025)

Improvements

• All plots in vignettes are now generated by the native SVG devicefor sharper appearance and fewer package dependencies (@nanxstats, #188).

Testing

• Add independent unit tests fortoInteger() (@DMuriuki, #186).

gsDesign 3.6.6 (February2025)

New features

• gsBoundSummary() gains a new argumentalpha to assemble a summary table with multiple efficacyboundaries (@keaven,#183).

Testing

• Add essential unit tests forgsSurvCalendar() (@keaven, #178).
• Refactor graphical tests withvdiffr::expect_doppelganger() (@nanxstats, #176).
• UseCODECOV_TOKEN to fix code coverage uploads (@jdblischak, #179).

Documentation

• Add more details to the parameterr for controllingnumerical integration grid points (@nanxstats, #181).

gsDesign 3.6.5 (November2024)

Improvements

• toInteger() (introduced in gsDesign 3.5.0) isupdated to match broader, non-gsDesign conventions for deriving integersample size and event counts (@keaven, #172).

  This update may result in different outputs compared to previousversions. Users who use this function should review the updated functiondocumentation (?toInteger) andvignette("toInteger") for details.

Testing

• Add snapshot tests foras_rtf() methods (@DMuriuki, #168).

Documentation

• Add thecph role to theAuthors@R fieldfollowing best practices (@nanxstats, #166).

gsDesign 3.6.4 (July 2024)

Improvements

We have made the spending function summary output more readable andinformative.

• Text summaries for spending functions with multiple parameters arenow properly formatted. For instance,a b = 0.5 1.5 is nowdisplayed asa = 0.5, b = 1.5 (@jdblischak, #162).
• Thesummary() method forsfLDOF() nolonger includes the redundantnone = 1 in its output (@jdblischak, #159).

Documentation

• Added a note about using a positive scalar forsfuparinsfLDOF() to create a generalized O’Brien-Flemingspending function (@keaven,52cc711,99996b).
• Improved math rendering in our pkgdown site vignettes by switchingto KaTeX, which is now supported in pkgdown 2.1.0 (@nanxstats, #161).
• Standardized vignette titles and headings by using h2 as the baselevel and adopting sentence case throughout (@nanxstats, #158).

gsDesign 3.6.3 (July 2024)

New features

• Implemented conditional error spending functionssfXG1(),sfXG2(), andsfXG3()based on Xi and Gallo (2019). Seevignette("ConditionalErrorSpending") for details andreproduced examples from the literature (@keaven, #147. Thanks,@xidongdxi, for comments onvignette).

Improvements

• EnhancedeEvents() with input validation to ensurelambda is notNULL (@keaven,97f629d).

Testing

• Added independent testing forgsSurvCalendar() (@myeongjong, #144).
• Expanded test coverage forgsBinomialExact() (@menglu2, #143).

gsDesign 3.6.2 (April 2024)

Documentation

• Add new vignette on conditional power and conditional error, seevignette("ConditionalPowerPlot") (beb2957,727fe20,57394fe).
• Fix roxygen2 warning and use magrittr pipes in vignette forconsistency (#131).

Testing

• Move independently programmed functions for validation as standardtest helper files (#130).

gsDesign 3.6.1 (February2024)

New features

• gsBoundSummary() now has theas_rtf()method implemented to generate RTF outputs for bound summary tables(@wangben718,#107).
• plotgsPower() gets new argumentsoffsetandtitleAnalysisLegend to enable more flexible andaccurate power plots (plottype = 2) (@jdblischak, #121, #123).

Improvements

• The plotting functions now usedplyr::reframe() toreplacedplyr::summarize() when performing groupedcumsum() (@jdblischak, #114).
• The plotting functions are updated to use the.datapronoun from rlang withggplot2::aes(). This simplifies thecode and follows the recommended practice when using ggplot2 in packages(@jdblischak,#124).
• hGraph() now uses namedguide argument inthescale_fill_manual() call to be compatible with ggplot23.5.0 (@teunbrand,#115).Note: this function has been deprecated andmoved to gMCPLite since gsDesign 3.4.0. It will be removed from gsDesignin a future version. Please usegMCPLite::hGraph()instead.

Documentation

• vignettes("SurvivalOverview") is updated with moredetails and minor corrections (@keaven, #126).
• Fix equation syntax in plotting function documentation to rendermath symbols properly (@keaven, #118).

gsDesign 3.6.0 (November2023)

Breaking changes

• gsSurv() andnSurv() have updated defaultvalues forT andminfup so that function callswith no arguments will run. Legacy code withT orminfup not explicitly specified could break (#105).

New features

• gsSurvCalendar() function added to enable groupsequential design for time-to-event outcomes using calendar timing ofinterim analysis specification (#105).
• as_rtf() method forgsBinomialExact()objects added, enable RTF table outputs for standard word processingsoftware (#102).

Improvements

• toBinomialExact() andgsBinomialExact():fix error checking in bound computations, improve documentation anderror messages (#105).
• print.gsSurv(): Improve the display of targeted events(very minor). The boundary crossing probability computations did notchange. The need is made evident by the addition of thetoInteger() function (#105).
• toInteger(): Fix the documentation and execution basedon theratio argument (#105).
• Update the vaccine efficacy, Poisson mixture model, and toIntegervignettes (#105).
• Standardize and improve roxygen2 documentation (#104).

gsDesign 3.5.0 (July 2023)

• sfPower() now allows a wider parameter range (0,15].
• toInteger() function added to convertgsDesign orgsSurv classes to integer samplesize and event counts.
• toBinomialExact() function added to converttime-to-event bounds to exact binomial for low event rate studies.
• Added “A Gentle Introduction to Group Sequential Design” vignettefor an introduction to asymptotics for group sequential design.
• as_table() andas_gt() methods forgsBinomialExact objects added, as described in the new“Binomial SPRT” vignette.
• Inplot.ssrCP(), thehat syntax in themathematical expression is revised, resolving labeling issues.
• ggplot2::qplot() usage replaced due to its deprecationin ggplot2 3.4.0.
• Link update for the gsDesign manual in the documentation, nowdirectly pointing to the gsDesign technical manual bookdownproject.
• Introduced a new hex sticker logo.

gsDesign 3.4.0 (October 2022)

• Removed restriction ongsCP() interim test statistic zi(#63).
• Removed gMCP dependency. Updated vignettes and linked to vignettesin gMCPLite (#69).
• Added deprecation warning tohGraph() and suggestedusinggMCPLite::hGraph() instead (#70).
• Moved ggplot2 fromDepends toImports(#56).

gsDesign 3.3.0 (May 2022)

• Addition of vignettes
  • Demonstrate cure model and calendar-based analysis timing fortime-to-event endpoint design
  • Vaccine efficacy design using spending bounds and exact binomialboundary crossing probabilities
• Minor fix to labeling in print.gsProbability
• Fixed error in sfStep
• Updates to reduce R CMD check and other minor issues

gsDesign 3.2.2 (January 2022)

• Useinherits() instead ofis() todetermine if an object is an instance of a class, when appropriate
• Correctly close graphics device in unit tests to avoid plot outputfile not found issues
• Minor fixes to hGraph() for multiplicity graphs
• Minor fix to nBinomial() when odds-ratio scale specified to resolveuser issue
• Minor changes to vignettes

gsDesign 3.2.1 (July 2021)

• Changed gt package usage in a vignette due to deprecated gtfunction
• Replied to minor comments from CRAN reviewer (no functionalityimpact)
• Minor update to DESCRIPTION citing Jennison and Turnbullreference

gsDesign 3.2.0 (January 2021)

• Substantially updated unit testing to increase code coverage above80%
• Updated error checking messages to print function where checkfails
• Removed dependencies on plyr packages
• Updated github actions

gsDesign 3.1.1 (May 2020)

• Vignettes updated
• AddedhGraph() to support ggplot2 versions ofmultiplicity graphs
• Eliminated unnecessary check fromsequentialPValue
• Targeted release to CRAN
• Removed dependencies on reshape2, plyr
• Updated continuous integration
• Updated license

gsDesign 3.1.0 (April 2019)

• Addition of pkgdown web site
• Updated unit testing to from RUnit to testthat
• Converted to roxygen2 generation of help files
• Converted vignettes to R Markdown
• Added Travis-CI and Appveyor support
• AddedsequentialPValue function
• Backwards compatible addition of spending time capabilities togsDesign andgsSurv

gsDesign 3.0-5 (January 2018)

• Registered C routines
• Fixed “gsbound”
• Replaced “array” by “rep” calls to avoidR CMD checkwarnings

gsDesign 3.0-4 (September2017)

• First Github-based release
• Cleaned up documentation fornBinomial1Sample()
• Updated documentation and code (including one default value for anargument) fornBinomial1Sample() to improve error handlingand clarity
• UpdatedsfLDOF() to generalize with rho parameter;still backwards compatible for Lan-DeMets O’Brien-Fleming

gsDesign 3.0-3

• Introduced spending time as a separate concept from information timeto enable concepts such as calendar-based spending functions. The onlyuser function changed is thegsDesign() function and thechange is the addition of the parametersusTime andlsTime; default behavior is backwards compatible.

gsDesign 3.0-2 (February2016)

• Simplified conditional power section of gsDesignManual.pdf in docdirectory
• Corrected basic calculation ingsCP()
• Eliminated deprecated ggplot2 functionopts()

gsDesign 3.0-1 (January 2016)

• More changes to comply with R standards (in NAMESPACE -importFrom statements - and DESCRIPTION - adding plyr toimports) ensuring appropriate references.
• Deleted link in documentation that no longer exists(gsBinomialExact.Rd).
• Last planned RForge-based release; moving to Github.

gsDesign 3.0-0 (December2015)

• Updated xtable extension to meet R standards for extensions.
• Fixedxtable.gsSurv andprint.gsSurv towork with 1-sided designs
• Update to calls to ggplot to replace show_guide (deprecated) withshow.legend arguments where used inggplot2::geom_text calls; no user impact
• Minor typo fixed insfLogistic help file
• Cleaned up “imports” and “depends” in an effort to be an R “goodcitizen”
• Registered S3 methods in NAMESPACE

gsDesign 2.9-4

• Minor edit to package description to comply with R standards

gsDesign 2.9-3 (November2014)

• AddedsfTrimmed as likely preferred spending functionapproach to skipping early or all interim efficacy analyses; this alsocan adjust bound when final analysis is performed with less than maximumplanned information. Updatedhelp(sfTrimmed) to demonstratethese capabilities.
• AddedsfGapped, which is primarily intended toeliminate futility analyses later in a study; seehelp(sfGapped) for an example
• Addedsummary.spendfn() to provide textual summary ofspending functions; this simplified the print function for gsDesignobjects
• AddedsfStep() which can be used to set an interimspend when the exact amount of information is unknown; an example of howthis can be misused is provided in the help file
• Fixed rounding so thatgsBoundSummary,xtable.gsSurv andsummary.gsDesign areconsistent forgsSurv objects