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EvidenceSynthesis: Synthesizing Causal Evidence in a Distributed Research Network

Routines for combining causal effect estimates and study diagnostics across multiple data sites in a distributed study, without sharing patient-level data. Allows for normal and non-normal approximations of the data-site likelihood of the effect parameter.

Version:1.1.0
Depends:survival, R (≥ 4.1.0)
Imports:dplyr,ggplot2 (≥ 4.0.0),ggdist,gridExtra,meta,EmpiricalCalibration,rJava,BeastJar (≥ 10.5.1),Cyclops (≥3.6.0),HDInterval,coda,rlang, methods
Suggests:knitr,rmarkdown,testthat,sn,tidyr
Published:2025-10-15
DOI:10.32614/CRAN.package.EvidenceSynthesis
Author:Martijn Schuemie [aut, cre], Marc A. Suchard [aut], Fan Bu [aut], Observational Health Data Science and Informatics [cph]
Maintainer:Martijn Schuemie <schuemie at ohdsi.org>
BugReports:https://github.com/OHDSI/EvidenceSynthesis/issues
License:Apache License 2.0
URL:https://ohdsi.github.io/EvidenceSynthesis/,https://github.com/OHDSI/EvidenceSynthesis
NeedsCompilation:no
SystemRequirements:Java (>= 8)
Materials:README,NEWS
In views:MetaAnalysis
CRAN checks:EvidenceSynthesis results

Documentation:

Reference manual:EvidenceSynthesis.html ,EvidenceSynthesis.pdf
Vignettes:Bayesian adaptive bias correction using profile likelihoods (source,R code)
Effect estimate using non-normal likelihood approximations (source,R code)
Code used in the video vignette (source,R code)

Downloads:

Package source: EvidenceSynthesis_1.1.0.tar.gz
Windows binaries: r-devel:EvidenceSynthesis_1.1.0.zip, r-release:EvidenceSynthesis_1.1.0.zip, r-oldrel:EvidenceSynthesis_1.1.0.zip
macOS binaries: r-release (arm64):EvidenceSynthesis_1.1.0.tgz, r-oldrel (arm64):EvidenceSynthesis_1.1.0.tgz, r-release (x86_64):EvidenceSynthesis_1.1.0.tgz, r-oldrel (x86_64):EvidenceSynthesis_1.1.0.tgz
Old sources: EvidenceSynthesis archive

Linking:

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