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combiroc: Selection and Ranking of Omics Biomarkers Combinations Made Easy

Provides functions and a workflow to easily and powerfully calculating specificity, sensitivity and ROC curves of biomarkers combinations. Allows to rank and select multi-markers signatures as well as to find the best performing sub-signatures, now also from single-cell RNA-seq datasets. The method used was first published as a Shiny app and described in Mazzara et al. (2017) <doi:10.1038/srep45477> and further described in Bombaci & Rossi (2019) <doi:10.1007/978-1-4939-9164-8_16>, and widely expanded as a package as presented in the bioRxiv pre print Ferrari et al. <doi:10.1101/2022.01.17.476603>.

Version:0.3.4
Depends:R (≥ 3.5.0)
Imports:tidyr,dplyr,ggplot2,gtools,pROC,stringr, stats, utils,moments
Suggests:testthat (≥ 3.0.0),knitr,markdown,rmarkdown,httr,Seurat
Published:2023-07-06
DOI:10.32614/CRAN.package.combiroc
Author:Ivan FerrariORCID iD [aut], Riccardo L. RossiORCID iD [aut, cre], Saveria MazzaraORCID iD [aut], Mauro BombaciORCID iD [ccp, ctb, dtc]
Maintainer:Riccardo L. Rossi <ric.rossi at gmail.com>
BugReports:https://github.com/ingmbioinfo/combiroc/issues
License:MIT + fileLICENSE
URL:https://doi.org/10.1101/2022.01.17.476603,https://github.com/ingmbioinfo/combiroc
NeedsCompilation:no
Language:en-US
Materials:README,NEWS
CRAN checks:combiroc results

Documentation:

Reference manual:combiroc.html ,combiroc.pdf
Vignettes:Quick guide to CombiROC (source,R code)
Single cell Combiroc tutorial (source,R code)

Downloads:

Package source: combiroc_0.3.4.tar.gz
Windows binaries: r-devel:combiroc_0.3.4.zip, r-release:combiroc_0.3.4.zip, r-oldrel:combiroc_0.3.4.zip
macOS binaries: r-release (arm64):combiroc_0.3.4.tgz, r-oldrel (arm64):combiroc_0.3.4.tgz, r-release (x86_64):combiroc_0.3.4.tgz, r-oldrel (x86_64):combiroc_0.3.4.tgz
Old sources: combiroc archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=combirocto link to this page.


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