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designit: Blocking and Randomization for Experimental Design

Intelligently assign samples to batches in order to reduce batch effects. Batch effects can have a significant impact on data analysis, especially when the assignment of samples to batches coincides with the contrast groups being studied. By defining a batch container and a scoring function that reflects the contrasts, this package allows users to assign samples in a way that minimizes the potential impact of batch effects on the comparison of interest. Among other functionality, we provide an implementation for OSAT score by Yan et al. (2012, <doi:10.1186/1471-2164-13-689>).

Version:0.5.0
Depends:R (≥ 4.1.0)
Imports:rlang (≥ 0.4.0),dplyr (≥ 1.0.0),purrr,ggplot2,scales,tibble,tidyr,assertthat,stringr,R6,data.table, stats
Suggests:testthat,roxygen2,pkgdown,knitr,markdown,rmarkdown,gt,bench,OSAT,tidyverse,printr,devtools (≥ 2.0.0),ggpattern,cowplot,bestNormalize,here
Published:2024-03-21
DOI:10.32614/CRAN.package.designit
Author:Iakov I. DavydovORCID iD [aut, cre, cph], Juliane Siebourg-PolsterORCID iD [aut, cph], Guido Steiner [aut, cph], Konrad RudolphORCID iD [ctb], Jitao David ZhangORCID iD [aut, cph], Balazs BanfaiORCID iD [aut, cph], F. Hoffman-La Roche [cph, fnd]
Maintainer:Iakov I. Davydov <iakov.davydov at roche.com>
BugReports:https://github.com/BEDApub/designit/issues
License:MIT + fileLICENSE
URL:https://bedapub.github.io/designit/,https://github.com/BEDApub/designit/
NeedsCompilation:no
Materials:README,NEWS
CRAN checks:designit results

Documentation:

Reference manual:designit.html ,designit.pdf
Vignettes:Basic example (source,R code)
Using custom shuffle schedule (source,R code)
In-vivo study design (source,R code)
designit: a flexible engine to generate experiment layouts (source,R code)
Nested dimension example (source,R code)
Optimizer examples (source,R code)
OSAT and scoring functions (source,R code)
Plate layouts (source,R code)
Shuffling with constraints (source,R code)

Downloads:

Package source: designit_0.5.0.tar.gz
Windows binaries: r-devel:designit_0.5.0.zip, r-release:designit_0.5.0.zip, r-oldrel:designit_0.5.0.zip
macOS binaries: r-release (arm64):designit_0.5.0.tgz, r-oldrel (arm64):designit_0.5.0.tgz, r-release (x86_64):designit_0.5.0.tgz, r-oldrel (x86_64):designit_0.5.0.tgz

Linking:

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