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cloneRate: Estimate Growth Rates from Phylogenetic Trees

Quickly estimate the net growth rate of a population or clone whose growth can be approximated by a birth-death branching process. Input should be phylogenetic tree(s) of clone(s) with edge lengths corresponding to either time or mutations. Based on coalescent results in Johnson et al. (2023) <doi:10.1093/bioinformatics/btad561>. Simulation techniques as well as growth rate methods build on prior work from Lambert A. (2018) <doi:10.1016/j.tpb.2018.04.005> and Stadler T. (2009) <doi:10.1016/j.jtbi.2009.07.018>.

Version:0.2.3
Depends:R (≥ 3.6.0)
Imports:ape (≥ 4.0), methods,Rcpp (≥ 0.12.0),Rmpfr (≥ 0.8),rstan (≥ 2.18.1),rstantools (≥ 2.3.1)
LinkingTo:BH (≥ 1.66.0),Rcpp (≥ 0.12.0),RcppEigen (≥ 0.3.3.3.0),RcppParallel (≥ 5.0.1),rstan (≥ 2.18.1),StanHeaders (≥2.18.0)
Suggests:car,covr,ggplot2,ggsurvfit,knitr, parallel,rmarkdown,survival,testthat (≥ 3.0.0)
Published:2023-09-22
DOI:10.32614/CRAN.package.cloneRate
Author:Brian JohnsonORCID iD [cre, aut, cph], Yubo Shuai [aut, cph], Jason SchweinsbergORCID iD [aut, cph], Kit CurtiusORCID iD [aut, cph]
Maintainer:Brian Johnson <brian.d.johnson97 at gmail.com>
BugReports:https://github.com/bdj34/cloneRate/issues
License:MIT + fileLICENSE
URL:https://github.com/bdj34/cloneRate,https://bdj34.github.io/cloneRate/
NeedsCompilation:yes
SystemRequirements:GNU make
Citation:cloneRate citation info
Materials:README,NEWS
CRAN checks:cloneRate results

Documentation:

Reference manual:cloneRate.html ,cloneRate.pdf
Vignettes:Analysis of human blood data (source,R code)
Validating growth rate estimates via simulation (source,R code)

Downloads:

Package source: cloneRate_0.2.3.tar.gz
Windows binaries: r-devel:cloneRate_0.2.3.zip, r-release:cloneRate_0.2.3.zip, r-oldrel:cloneRate_0.2.3.zip
macOS binaries: r-release (arm64):cloneRate_0.2.3.tgz, r-oldrel (arm64):cloneRate_0.2.3.tgz, r-release (x86_64):cloneRate_0.2.3.tgz, r-oldrel (x86_64):cloneRate_0.2.3.tgz

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=cloneRateto link to this page.


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