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ruv: Detect and Remove Unwanted Variation using Negative Controls

Implements the 'RUV' (Remove Unwanted Variation) algorithms. These algorithms attempt to adjust for systematic errors of unknown origin in high-dimensional data. The algorithms were originally developed for use with genomic data, especially microarray data, but may be useful with other types of high-dimensional data as well. These algorithms were proposed in Gagnon-Bartsch and Speed (2012) <doi:10.1093/nar/gkz433>, Gagnon-Bartsch, Jacob and Speed (2013), and Molania, et. al. (2019) <doi:10.1093/nar/gkz433>. The algorithms require the user to specify a set of negative control variables, as described in the references. The algorithms included in this package are 'RUV-2', 'RUV-4', 'RUV-inv', 'RUV-rinv', 'RUV-I', and RUV-III', along with various supporting algorithms.

Version:0.9.7.1
Imports:stats,ggplot2,scales,gridExtra
Suggests:shiny,colourpicker
Published:2019-08-30
DOI:10.32614/CRAN.package.ruv
Author:Johann Gagnon-Bartsch
Maintainer:Johann Gagnon-Bartsch <johanngb at umich.edu>
License:GPL-2 |GPL-3 [expanded from: GPL]
URL:http://www-personal.umich.edu/~johanngb/ruv/
NeedsCompilation:yes
CRAN checks:ruv results

Documentation:

Reference manual:ruv.html ,ruv.pdf

Downloads:

Package source: ruv_0.9.7.1.tar.gz
Windows binaries: r-devel:ruv_0.9.7.1.zip, r-release:ruv_0.9.7.1.zip, r-oldrel:ruv_0.9.7.1.zip
macOS binaries: r-release (arm64):ruv_0.9.7.1.tgz, r-oldrel (arm64):ruv_0.9.7.1.tgz, r-release (x86_64):ruv_0.9.7.1.tgz, r-oldrel (x86_64):ruv_0.9.7.1.tgz
Old sources: ruv archive

Reverse dependencies:

Reverse imports:MBECS,missMethyl,PhosR,scMerge,standR
Reverse suggests:NanoTube

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=ruvto link to this page.


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