clinDR: Simulation and Analysis Tools for Clinical Dose ResponseModeling
Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) <doi:10.1080/19466315.2014.924876> and Thomas and Roy (2016) <doi:10.1080/19466315.2016.1256229> Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) <doi:10.1177/0962280216684528> are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.
| Version: | 2.5.2 |
| Depends: | R (≥ 3.5.0),rstan (≥ 2.17.3),shiny |
| Imports: | foreach, graphics,DoseFinding, stats,mvtnorm, utils, parallel,doParallel,ggplot2,tidyr,purrr,tibble,dplyr,glue,waiter |
| Published: | 2025-10-02 |
| DOI: | 10.32614/CRAN.package.clinDR |
| Author: | Neal Thomas [aut, cre], Jing Wu [aut], Mike K. Smith [aut] |
| Maintainer: | Neal Thomas <snthomas99 at gmail.com> |
| License: | GPL-2 |GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Materials: | NEWS |
| In views: | Pharmacokinetics |
| CRAN checks: | clinDR results |
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