fcfdr: Flexible cFDR
Provides functions to implement the Flexible cFDR (Hutchinson et al. (2021) <doi:10.1371/journal.pgen.1009853>) and Binary cFDR (Hutchinson et al. (2021) <doi:10.1101/2021.10.21.465274>) methodologies to leverage auxiliary data from arbitrary distributions, for example functional genomic data, with GWAS p-values to generate re-weighted p-values.
| Version: | 1.0.0 |
| Depends: | R (≥ 3.5.0) |
| Imports: | locfdr,MASS,ggplot2,cowplot,fields,dplyr,spatstat.geom,polyCub,hexbin,bigsplines,data.table, grDevices,Hmisc |
| Suggests: | stats,knitr,rmarkdown,digest,testthat (≥ 3.0.0) |
| Published: | 2022-02-07 |
| DOI: | 10.32614/CRAN.package.fcfdr |
| Author: | Anna Hutchinson [aut, cre], Chris Wallace [aut], Thomas Willis [ctb, aut], James Liley [ctb] |
| Maintainer: | Anna Hutchinson <annahutchinson1995 at gmail.com> |
| License: | MIT + fileLICENSE |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| CRAN checks: | fcfdr results |
Documentation:
| Reference manual: | fcfdr.html ,fcfdr.pdf |
| Vignettes: | Extra Information (source,R code) Introductory vignette (source,R code) LDAK vignette (source,R code) T1D Application (source,R code) |
Downloads:
| Package source: | fcfdr_1.0.0.tar.gz |
| Windows binaries: | r-devel:fcfdr_1.0.0.zip, r-release:fcfdr_1.0.0.zip, r-oldrel:fcfdr_1.0.0.zip |
| macOS binaries: | r-release (arm64):fcfdr_1.0.0.tgz, r-oldrel (arm64):fcfdr_1.0.0.tgz, r-release (x86_64):fcfdr_1.0.0.tgz, r-oldrel (x86_64):fcfdr_1.0.0.tgz |
Linking:
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