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mashr: Multivariate Adaptive Shrinkage

Implements the multivariate adaptive shrinkage (mash) method of Urbut et al (2019) <doi:10.1038/s41588-018-0268-8> for estimating and testing large numbers of effects in many conditions (or many outcomes). Mash takes an empirical Bayes approach to testing and effect estimation; it estimates patterns of similarity among conditions, then exploits these patterns to improve accuracy of the effect estimates. The core linear algebra is implemented in C++ for fast model fitting and posterior computation.

Version:0.2.79
Depends:R (≥ 3.3.0),ashr (≥ 2.2-22)
Imports:assertthat, utils, stats,plyr,rmeta,Rcpp (≥ 1.0.8),mvtnorm,abind,softImpute
LinkingTo:Rcpp,RcppArmadillo,RcppGSL (≥ 0.3.8)
Suggests:MASS,REBayes,corrplot (≥ 0.90),testthat,kableExtra,knitr,rmarkdown,profmem,flashier,ebnm
Published:2023-10-18
DOI:10.32614/CRAN.package.mashr
Author:Matthew Stephens [aut], Sarah Urbut [aut], Gao Wang [aut], Yuxin Zou [aut], Yunqi Yang [ctb], Sam Roweis [cph], David Hogg [cph], Jo Bovy [cph], Peter Carbonetto [aut, cre]
Maintainer:Peter Carbonetto <peter.carbonetto at gmail.com>
BugReports:https://github.com/stephenslab/mashr/issues
License:BSD_3_clause + fileLICENSE
Copyright:file COPYRIGHTS
mashr copyright details
URL:https://github.com/stephenslab/mashr
NeedsCompilation:yes
Citation:mashr citation info
Materials:README
CRAN checks:mashr results

Documentation:

Reference manual:mashr.html ,mashr.pdf
Vignettes:using mashr for eQTL studies (source,R code)
mashr intro with correlations (source,R code)
mashr intro with data-driven covariances (source,R code)
mashr intro (source,R code)
mashnocommonbaseline intro (source,R code)
mashcommonbaseline intro (source,R code)
Sample from mash posteriors (source,R code)
mashr simulation with non-canonical matrices (source,R code)

Downloads:

Package source: mashr_0.2.79.tar.gz
Windows binaries: r-devel:mashr_0.2.79.zip, r-release:mashr_0.2.79.zip, r-oldrel:mashr_0.2.79.zip
macOS binaries: r-release (arm64):mashr_0.2.79.tgz, r-oldrel (arm64):mashr_0.2.79.tgz, r-release (x86_64):mashr_0.2.79.tgz, r-oldrel (x86_64):mashr_0.2.79.tgz
Old sources: mashr archive

Reverse dependencies:

Reverse imports:dreamlet,limorhyde2,multistateQTL

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=mashrto link to this page.


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