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iAdapt: Two-Stage Adaptive Dose-Finding Clinical Trial Design

Simulate and implement early phase two-stage adaptive dose-finding design for binary and quasi-continuous toxicity endpoints. See Chiuzan et al. (2018) for further reading <doi:10.1080/19466315.2018.1462727>.

Version:2.0.1
Depends:R (≥ 3.5.0),shiny,shinydashboard
Imports:Matrix, grDevices, utils
Suggests:knitr,rmarkdown
Published:2021-08-06
DOI:10.32614/CRAN.package.iAdapt
Author:Alyssa Vanderbeek [aut, cre], Laura Cosgrove [ctb], Elizabeth Garrett-Mayer [ctb], Cody Chiuzan [ctb]
Maintainer:Alyssa Vanderbeek <vanderbeekam at gmail.com>
License:LGPL-3
NeedsCompilation:no
Materials:README
In views:ClinicalTrials
CRAN checks:iAdapt results

Documentation:

Reference manual:iAdapt.html ,iAdapt.pdf
Vignettes:Trial simulation with binary toxicity measure (source,R code)
Trial implementation (source,R code)
Trial simulation with quasi-continuous toxicity measure (source,R code)

Downloads:

Package source: iAdapt_2.0.1.tar.gz
Windows binaries: r-devel:iAdapt_2.0.1.zip, r-release:iAdapt_2.0.1.zip, r-oldrel:iAdapt_2.0.1.zip
macOS binaries: r-release (arm64):iAdapt_2.0.1.tgz, r-oldrel (arm64):iAdapt_2.0.1.tgz, r-release (x86_64):iAdapt_2.0.1.tgz, r-oldrel (x86_64):iAdapt_2.0.1.tgz
Old sources: iAdapt archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=iAdaptto link to this page.


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