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Seurat: Tools for Single Cell Genomics

A toolkit for quality control, analysis, and exploration of single cell RNA sequencing data. 'Seurat' aims to enable users to identify and interpret sources of heterogeneity from single cell transcriptomic measurements, and to integrate diverse types of single cell data. See Satija R, Farrell J, Gennert D, et al (2015) <doi:10.1038/nbt.3192>, Macosko E, Basu A, Satija R, et al (2015) <doi:10.1016/j.cell.2015.05.002>, Stuart T, Butler A, et al (2019) <doi:10.1016/j.cell.2019.05.031>, and Hao, Hao, et al (2020) <doi:10.1101/2020.10.12.335331> for more details.

Version:5.4.0
Depends:R (≥ 4.0.0), methods,SeuratObject (≥ 5.0.2)
Imports:cluster,cowplot,fastDummies,fitdistrplus,future,future.apply,generics (≥ 0.1.3),ggplot2 (≥ 3.3.0),ggrepel,ggridges, graphics, grDevices, grid,httr,ica,igraph,irlba,jsonlite,KernSmooth,lifecycle,lmtest,MASS,Matrix (≥1.5-0),matrixStats,miniUI,patchwork,pbapply,plotly (≥4.9.0),png,progressr,RANN,RColorBrewer,Rcpp (≥ 1.0.7),RcppAnnoy (≥ 0.0.18),RcppHNSW,reticulate,rlang,ROCR,RSpectra,Rtsne,scales,scattermore (≥ 1.2),sctransform (≥0.4.1),shiny,spatstat.explore,spatstat.geom, stats,tibble, tools, utils,uwot (≥ 0.1.10)
LinkingTo:Rcpp (≥ 0.11.0),RcppEigen,RcppProgress
Suggests:ape,arrow,base64enc,Biobase,BiocGenerics, BPCells,data.table,DESeq2,DelayedArray,enrichR,GenomicRanges,GenomeInfoDb,glmGamPoi,ggrastr,harmony,hdf5r,IRanges,leidenbase,limma,magrittr,MAST,metap,mixtools,monocle, presto,rsvd,R.utils,Rfast2,rtracklayer,S4Vectors,sf (≥1.0.0),sp,SingleCellExperiment,SummarizedExperiment,testthat,VGAM
Published:2025-12-14
DOI:10.32614/CRAN.package.Seurat
Author:Andrew ButlerORCID iD [ctb], Saket ChoudharyORCID iD [ctb], David CollinsORCID iD [ctb], Charlotte DarbyORCID iD [ctb], Jeff Farrell [ctb], Isabella GrabskiORCID iD [ctb], Christoph HafemeisterORCID iD [ctb], Yuhan HaoORCID iD [ctb], Austin HartmanORCID iD [ctb], Paul HoffmanORCID iD [ctb], Jaison JainORCID iD [ctb], Longda JiangORCID iD [ctb], Madeline KowalskiORCID iD [ctb], Skylar Li [ctb], Brian Zhang [ctb], Gesmira MollaORCID iD [ctb], Efthymia PapalexiORCID iD [ctb], Patrick Roelli [ctb], Rahul SatijaORCID iD [aut, cre], Karthik Shekhar [ctb], Anagha ShenoyORCID iD [ctb], Avi SrivastavaORCID iD [ctb], Tim StuartORCID iD [ctb], Kristof TorkenczyORCID iD [ctb], Brian Zhang [ctb], Shiwei ZhengORCID iD [ctb], Satija Lab and Collaborators [fnd]
Maintainer:Rahul Satija <seurat at nygenome.org>
BugReports:https://github.com/satijalab/seurat/issues
License:MIT + fileLICENSE
URL:https://satijalab.org/seurat,https://github.com/satijalab/seurat
NeedsCompilation:yes
Additional_repositories:https://satijalab.r-universe.dev,https://bnprks.r-universe.dev
Citation:Seurat citation info
Materials:README,NEWS
In views:Omics
CRAN checks:Seurat results

Documentation:

Reference manual:Seurat.html ,Seurat.pdf

Downloads:

Package source: Seurat_5.4.0.tar.gz
Windows binaries: r-devel:Seurat_5.4.0.zip, r-release:Seurat_5.3.1.zip, r-oldrel:Seurat_5.4.0.zip
macOS binaries: r-release (arm64):Seurat_5.4.0.tgz, r-oldrel (arm64):Seurat_5.4.0.tgz, r-release (x86_64):Seurat_5.4.0.tgz, r-oldrel (x86_64):Seurat_5.4.0.tgz
Old sources: Seurat archive

Reverse dependencies:

Reverse depends:CACIMAR,CelliD,ReactomeGSA.data,scAnnotatR,SCArray.sat,scCustomize,SCdeconR
Reverse imports:AnanseSeurat,APackOfTheClones,bbknnR,blase,CAESAR.Suite,CatsCradle,CDI,ClustAssess,ClusterFoldSimilarity,coFAST,COTAN,CSOA,CuratedAtlasQueryR,decontX,Dino,DOtools,DR.SC,DWLS,GeneNMF,ggsc,ggsector,HetSeq,infercnv,mixhvg,MOSim,nebula,partCNV,pipeComp,Platypus,PopComm,PRECAST,ProFAST,RegionalST,RepeatedHighDim,rPanglaoDB,scAnnotate,scaper,scBFA,scBubbletree,scCB2,sccca,sccore,scDataviz,scDiffCom,scDotPlot,scGate,scGOclust,scMappR,scperturbR,scPipeline,scpoisson,scRNAseqApp,scRNAstat,scStability,scTreeViz,SeuratExplorer,SignacX,SingleCellComplexHeatMap,singleCellTK,SlideCNA,SlimR,SoupX,SpaCCI,Spaniel,SPECK,speckle,SpotClean,stJoincount,stPipe,STREAK,tidyseurat,XYomics
Reverse suggests:anglemania,anndataR,ASURAT,Banksy,BayesSpace,Canek,CIARA,ClusterGVis,clustifyrdatahub,clustree,combiroc,conos,consICA,countland,CRMetrics,CytoSimplex,DamageDetective,DCATS,decoupleR,demuxSNP,DIscBIO,dittoSeq,dominoSignal,dorothea,dyngen,easybio,EasyCellType,EpiMix,escape,escheR,FEAST,fgsea,GeomxTools,grandR,harmony,HCATonsilData,HVP,immundata,jazzPanda,looking4clusters,M3Drop,mLLMCelltype,MOFA2,monocle,muscData,mxfda,myTAI,Nebulosa,nipalsMCIA,PoweREST,progeny,ReactomeGSA,RESET,rliger,rSWeeP,scGraphVerse,schex,scLANE,SCORPIUS,SCpubr,scRepertoire,scTensor,SETA,Signac,SimBenchData,SimBu,SpaNorm,SpatialDecon,SpatialFeatureExperiment,SuperCell,SuperCellCyto,TAPseq,TCGAbiolinks,tidybulk,treefit,tricycle,UCell,VAM,visiumStitched

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=Seuratto link to this page.


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