gemma2: GEMMA Multivariate Linear Mixed Model
Fits a multivariate linear mixed effects model that uses a polygenic term, after Zhou & Stephens (2014) (<https://www.nature.com/articles/nmeth.2848>). Of particular interest is the estimation of variance components with restricted maximum likelihood (REML) methods. Genome-wide efficient mixed-model association (GEMMA), as implemented in the package 'gemma2', uses an expectation-maximization algorithm for variance components inference for use in quantitative trait locus studies.
| Version: | 0.1.3 |
| Imports: | methods,Matrix |
| Suggests: | covr,testthat,knitr,rmarkdown,readr |
| Published: | 2020-10-24 |
| DOI: | 10.32614/CRAN.package.gemma2 |
| Author: | Frederick Boehm [aut, cre] |
| Maintainer: | Frederick Boehm <frederick.boehm at gmail.com> |
| BugReports: | https://github.com/fboehm/gemma2/issues |
| License: | MIT + fileLICENSE |
| URL: | https://github.com/fboehm/gemma2 |
| NeedsCompilation: | no |
| Language: | en-US |
| Materials: | README,NEWS |
| CRAN checks: | gemma2 results |
Documentation:
| Reference manual: | gemma2.html ,gemma2.pdf |
| Vignettes: | Comparing gemma2 output with that of Zhou's GEMMA (source,R code) |
Downloads:
| Package source: | gemma2_0.1.3.tar.gz |
| Windows binaries: | r-devel:gemma2_0.1.3.zip, r-release:gemma2_0.1.3.zip, r-oldrel:gemma2_0.1.3.zip |
| macOS binaries: | r-release (arm64):gemma2_0.1.3.tgz, r-oldrel (arm64):gemma2_0.1.3.tgz, r-release (x86_64):gemma2_0.1.3.tgz, r-oldrel (x86_64):gemma2_0.1.3.tgz |
| Old sources: | gemma2 archive |
Reverse dependencies:
| Reverse imports: | qtl2pleio |
Linking:
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