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CB2: CRISPR Pooled Screen Analysis using Beta-Binomial Test

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Version:1.3.6
Depends:R (≥ 3.5.0)
Imports:Rcpp,metap,magrittr,dplyr,tibble,stringr,ggplot2,tidyr,glue,pheatmap, tools,readr, parallel,R.utils
LinkingTo:Rcpp,RcppArmadillo
Suggests:testthat,knitr,rmarkdown
Published:2025-10-01
DOI:10.32614/CRAN.package.CB2
Author:Hyun-Hwan Jeong [aut, cre]
Maintainer:Hyun-Hwan Jeong <hyunhwanjeong at icloud.com>
License:MIT + fileLICENSE
NeedsCompilation:yes
Materials:README
In views:Omics
CRAN checks:CB2 results

Documentation:

Reference manual:CB2.html ,CB2.pdf
Vignettes:Handling the input matrix in CB2 (source,R code)
CB2 Tutorial (source,R code)

Downloads:

Package source: CB2_1.3.6.tar.gz
Windows binaries: r-devel:CB2_1.3.6.zip, r-release:CB2_1.3.6.zip, r-oldrel:CB2_1.3.6.zip
macOS binaries: r-release (arm64):CB2_1.3.6.tgz, r-oldrel (arm64):CB2_1.3.6.tgz, r-release (x86_64):CB2_1.3.6.tgz, r-oldrel (x86_64):CB2_1.3.6.tgz
Old sources: CB2 archive

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=CB2to link to this page.


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