'Align-GVGD' ('A-GVGD') is a method to predict the impact of 'missense' substitutions based on the properties of amino acid side chains and protein multiple sequence alignments <doi:10.1136/jmg.2005.033878>. 'A-GVGD' is an extension of the original 'Grantham' distance to multiple sequence alignments. This package provides an alternative R implementation to the web version found on <http://agvgd.hci.utah.edu/>.
| Version: | 0.1.2 |
| Depends: | R (≥ 2.10) |
| Imports: | crayon,dplyr,glue,grantham,magrittr,purrr,rlang,seqinr,stringr,tibble,tidyr,vctrs |
| Suggests: | rmarkdown,covr,testthat (≥ 3.0.0) |
| Published: | 2022-09-10 |
| DOI: | 10.32614/CRAN.package.agvgd |
| Author: | Ramiro Magno [aut, cre], Isabel Duarte [aut], Ana-Teresa Maia [aut], CINTESIS [cph, fnd] |
| Maintainer: | Ramiro Magno <ramiro.magno at gmail.com> |
| BugReports: | https://github.com/maialab/agvgd/issues |
| License: | MIT + fileLICENSE |
| URL: | https://maialab.org/agvgd/,https://github.com/maialab/agvgd |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| In views: | Omics |
| CRAN checks: | agvgd results |