tout: Optimal Sample Size and Progression Criteria for Three-OutcomeTrials
Find the optimal decision rules (AKA progression criteria) and sample size for clinical trials with three (stop/pause/go) outcomes. Both binary and continuous endpoints can be accommodated, as can cases where an adjustment is planned following a pause outcome. For more details see Wilson et al. (2024) <doi:10.1186/s12874-024-02351-x>.
| Version: | 1.0.3 |
| Suggests: | knitr,rmarkdown,testthat (≥ 3.0.0),vdiffr |
| Published: | 2025-11-07 |
| DOI: | 10.32614/CRAN.package.tout |
| Author: | Duncan Wilson [aut, cre, cph] |
| Maintainer: | Duncan Wilson <d.t.wilson at leeds.ac.uk> |
| BugReports: | https://github.com/DTWilson/tout/issues |
| License: | MIT + fileLICENSE |
| URL: | https://github.com/DTWilson/tout,https://dtwilson.github.io/tout/ |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| CRAN checks: | tout results |
Documentation:
| Reference manual: | tout.html ,tout.pdf |
| Vignettes: | Three-outcome clinical trial design (tout) (source,R code) |
Downloads:
| Package source: | tout_1.0.3.tar.gz |
| Windows binaries: | r-devel:tout_1.0.3.zip, r-release:tout_1.0.3.zip, r-oldrel:tout_1.0.3.zip |
| macOS binaries: | r-release (arm64):tout_1.0.3.tgz, r-oldrel (arm64):tout_1.0.3.tgz, r-release (x86_64):tout_1.0.3.tgz, r-oldrel (x86_64):tout_1.0.3.tgz |
Linking:
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