David Crane (born August 13, 1957 in Philadelphia) is an American writer and producer. He is one of the creators of the TV sitcom Friends, along with his longtime friend Marta Kauffman.

Crane attended Harriton High school in Rosemont, Pennsylvania, and received his bachelor's degree from Brandeis University. He is the son of Philadelphia news anchor Gene Crane and his first wife Joan.

He and Jeffrey Klarik created the 2006 ensemble sitcom, The Class.

In 2011, it was announced that Crane along with Jeffrey Klarik (producer of Mad About You) have created a new sitcom made for the BBC. Airing first in the US on Showtime on Sunday January 9, 2011 at 9:30 pm and then on BBC Two on Monday January 10, 2011 at 10 pm. It is called Episodes and features Friends star Matt LeBlanc and Green Wing's Stephen Mangan and Tamsin Greig.