Mileena is a player and occasional boss character from the Mortal Kombat series of fighting games. A dual sai-wielding assassin, she acts as the evil twin and magenta palette swap of Princess Kitana in Mortal Kombat II in 1993. She has been promoted throughout the Mortal Kombat games as its semi-ironic sex symbol, especially since Mortal Kombat: Deception when she began a pattern of wearing more revealing outfits.

The series' 2011 reboot made her even more psychologically unstable, not to mention cannibalistic, and her resemblance to her sister has greatly diminished. In the backstory of Mortal Kombat X, Mileena is the sole surviving heir of Shao Kahn and vies for the Outworld throne with the warlord Kotal Kahn. Despite some criticism for her character designs, Mileena has become one of the most popular characters in the series.